Steven (Jinpu) Cai

Steven (Jinpu) Cai

Focusing on Bioinformatics and AI for Drug Discovery and Development.

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Publications

  • Cheng Wang, *Jinpu Cai* (Co-first), Chongxiao Mao, Yuxuan Wang, Xinzhu Jiang, Yunhao Qiao, Luqi Yang, Luting Zhou, Qiuyu Lian, Hongyi Xin.
    InfoGlobe: Local-and-Global Information-Preserving Statistical Manifold Learning for Single-Cell Transcriptomics, ICML, 2026 (Under Review).

  • *Jinpu Cai*, Yuxuan Wang, Yunhao Qiao, Cheng Wang, Ziqi Rong, Luting Zhou, Haoyang Liu, Meng Jiang, Hongbin Shen, Jingyi Jessica Li, Hongyi Xin.
    Information Geometry Reconciles Discrete and Continuous Variation in Single-Cell and Spatial Transcriptomic Analysis, RECOMB, 2026.

  • *Jinpu Cai*, Xiaorui Liu, Ziqi Rong, Luting Zhou, Xinzhu Jiang, Pengcheng Xu, Rui Gao, Hui Cheng, Luqi Yang, Yu Zhao, Bing He, Jianhua Yao, Shyam Prabhakar, Qiuyu Lian, Liang Chen, Hongyi Xin.
    Mutual Exclusive Gene Expression Reveals a Stress-Induced Compensatory Role of Taurine Uptake in Dilated Cardiomyopathy, Briefings in Bioinformatics, 2025.

  • *Jinpu Cai*, Ziqi Rong, Luting Zhou, Jingyi Jessica Li, Hongyi Xin.
    Harmonizing Qualitative and Quantitative Analyses in scRNA-seq via Information Geometry, Briefings in Bioinformatics, 2025.

  • *Jinpu Cai*, Yuyang Xu, Wen Zhang, Shiying Ding, Yuewei Sun, Jingyi Lyu, Meiyu Duan, Shuai Liu, Lan Huang, Fengfeng Zhou.
    A Comprehensive Comparison of Residue-Level Methylation Levels with the Regression-Based Gene-Level Methylation Estimations by ReGear, Briefings in Bioinformatics, 2021.

  • Xiaorui Liu*, *Jinpu Cai* (Co-first), …, Hang Gao, Yibo Zhang, Xinjie Xu, Xiangjie Li, Luting Zhou, Hui Cheng, Luqi Yang, Liang Chen, Hongyi Xin, Shengshou Hu.
    Single-Nuclei Transcriptome Profiling of Human Hearts with Different Subtype (Genotype) of Arrhythmogenic Cardiomyopathy Identified Common Mediator of Myocardial Adipogenesis, In preparation, 2025.

  • Ziqi Rong, *Jinpu Cai* (Co-first), Jiahao Qiu, Pengcheng Xu, Lana X. Garmire, Qiuyu Lian, Hongyi Xin.
    L2 Normalization and Geodesic Distance for Enhanced Information Preservation in Visualizing High-Dimensional Single-Cell Sequencing Data, ACM-BCB 2024 (    Best Paper Award*), 2024.

  • Ziqi Rong, *Jinpu Cai* (Co-first), Jiahao Qiu, Pengcheng Xu, Lana X. Garmire, Qiuyu Lian, Hongyi Xin.
    Informative Visualization of Single-Cell Sequencing Data with Geodesic Distance on Normalization Space, *Big Data Mining and Analytics    , 2025.

  • Pengcheng Xu*, *Jinpu Cai* (Co-first), Yulin Gao, Ziqi Rong, Hongyi Xin.
    MIRACLE: Multi-task Learning Based Interpretable Regulation of Autoimmune Diseases through Common Latent Epigenetics, bioRxiv, 2025.

  • Luqi Yang, Zhenwei Huang, *Jinpu Cai*, Hongyi Xin.
    Gene-First Identity Construction for Robust Cell Identification in Single-Cell Transcriptomics, RECOMB, 2026.

  • Qiuyu Lian, Jianzhu Ma, Kui Hua, Ziqi Rong, *Jinpu Cai*, Xinzhu Jiang, Jieli Zhou, Jiaying Xu, Zhiyuang Zhang, Li Fan, Henry Zou, Xiaoling Huang, Qi Yan, Jin Gu, Xuegong Zhang, Hong-Bin Shen, John Marioni, Kong Chen, Hongyi Xin.
    Total-mRNA-aware Analysis for Droplet-Based Single Cell Sequencing, bioRxiv, 2022.

  • Fengxin Li, Ziye Luo, Jingyu Huang, Lingzhan Wang, *Jinpu Cai*, Yongping Huang.
    AlTwo: Vehicle Recognition in Foggy Weather Based on Two-Step Recognition Algorithm, International Symposium on Neural Networks, 2020.